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Load:
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1. komponenta
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20 |
* Load is given in academic hour (1 academic hour = 45 minutes)
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Description:
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INDICATIVE CONTENT OF THE COURSE / MODULE
Transition-catalyzed reactions: Pd-, Ni- and Cu-catalyzed cross-coupling reactions; Asymmetric allyl alkylations; Methods of metathesis in organic chemistry: Types of metathesis reactions; Alkane, alkane and alkyne metathesis reactions; Methods of green organic chemistry: Application of microwaves in sustainable organic chemistry; Microwave-assisted heterocycle synthesis; Photochemical and photocatalytic organic synthesis; Solid state organic synthesis. The importance of the application of modern methods in the synthesis of the target compound with reference to the reaction mechanism. The importance of green organic chemistry methods instead of the given methods of conventional synthesis with the aim of their application in industry and technology. Combining modern methods in the synthesis of a given compound.
DESCRIPTION OF TEACHING METHODS
Teaching methods individually tailored to the student: lectures and / or consultations.
DESCRIPTION OF THE MANNER OF PERFORMANCE OF OBLIGATIONS
Preparation of an independent seminar paper related to a topic of scientific or professional interest for a doctoral student. Presentation of seminar paper. Written exam.
Learning outcomes for the course Modern trends in organic synthesis
1. To compare critically the cross-coupling reactions catalysed by transition metals (Pd, Ni and Cu).
2. To discuss the metathesis reactions of alkanes, alkenes and alkynes.
3. To recommend the application of an appropriate modern method for the synthesis of target compound with reference to the reaction mechanism.
4. To conceive methods of green organic chemistry rather than the selected methods of conventional synthesis with a view to their application in industry and technology.
5. To present the examples of combining modern methods of synthesis of a given compound to competent audience.
LEARNING OUTCOMES AT PROGRAM LEVEL
1. To systematise knowledge, skills and competences for the respective field and academic area of the programme of study
2. To evaluate the skills and methods for experimental and theoretical research relating to the respective field and academic area of the programme of study
LITERATURE:
Pierre Vogel, Kendall N. Houk. (2019). Organic Chemistry: Theory, Reactivity and Mechanisms in Modern Synthesis. Wiley, Manchester, UK
Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry.
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Learning outcomes:
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- To compare critically the cross-coupling reactions catalysed by transition metals (Pd, Ni and Cu).
- To discuss the metathesis reactions of alkanes, alkenes and alkynes.
- To recommend the application of an appropriate modern method for the synthesis of target compound with reference to the reaction mechanism.
- To conceive methods of green organic chemistry rather than the selected methods of conventional synthesis with a view to their application in industry and technology.
- To present the examples of combining modern methods of synthesis of a given compound to competent audience.
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Literature:
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Organic Chemistry: Theory, Reactivity and Mechanisms in Modern Synthesis, Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry., Pierre Vogel, Kendall N. Houk, Wiley, Manchester, UK, 2019.
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