Course objectives:
The main objective of the course is to familiarize students with the basic principles of modern organic chemistry, understanding the structure-activity relationship of organic compounds and application of methods in syntheses of organic compounds in the biosciences and industry.
Learning outcomes at the level of the study programme to which the course contributes:
1. Ability to identify and solve qualitative problems by applying of appropriate chemical principles and theories,
2. Competences in the estimation, interpretation and synthesis of chemical information and data,
3. Performing of standard laboratory techniques and the use of adequate instrumentation that is used in the preparative purposes and organic systems,
4. Results interpretation of laboratory observations and measurements, their meanings and connection with corresponding theory,
5. Management and planning of time skills, the ability for independent work
Expected learning outcomes at the level of the course (4-10 learning outcomes):
1. To analyze the structure of the compounds of carbon, organic compounds and define the nature of chemical bonds in organic molecules based on molecular orbital theory and hybrid atomic orbitals,
2. To define the basic types of organic reactions and explain their reaction mechanisms with the recognition of reactive intermediates in reaction,
3. To idetify functional groups in molecules and define corresponding class of compounds, to apply IUPAC rules for naming of organic compounds,
4. To explain conformations of alkanes and cycloalkanes, define and name isomers,
5. To define reactions of alkanes, alkenes, alkynes, alcohols, ethers, reactions in which alky halides, alkenes, alkynes, alcohols and ethers are involved,
6. To explain radical reactions.
COURSE CONTENT:
1. CARBON COMPOUNDS AND INTRODUCTION TO STRUCTURAL THEORY OF ORGANIC CHEMISTRY: introduction to structural theory: the empirical and structural molecular formulas, isomers, tetrahedral structure of methane; chemical bonds-the octet rule, ionic and covalent bonds, Lewis structures, resonance; quantum mechanics, atomic and molecular orbitals; structure of methane and ethane: sp3-hybiridisation; structure of ethene: sp2-hybiridisation, cis-trans isomerism; structure of ethyne: sp-hybridisation.
Seminar examples for determination of isomer structures, covalent and ionic bonds in the molecule, Lewis structures, resonance structures
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1. T. W. G.Solomon, C. B. Fryhle, Organic Chemistry, J. Wiley, 2004.,
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2. J. Clayden, N. Greeves, S. Warren, P. Wothers, Organic Chemistry, Oxford University Press, Oxford, 2001.,
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L. G. Wade, Organic Chemistry, Pearson Education Ltd., London, 2006.,
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