1. komponenta

Lecture type	Total
Lectures	30
Seminar	30

* Load is given in academic hour (1 academic hour = 45 minutes)

Course objectives:
To acquire theoretical and practical knowledge of direct and indirect effects of xenobiotics on the environment, all living organisms, and their relationship with inanimate matter.

Course content (syllabus):
WEEK 1. Introduction to ecotoxicology. Definitions of terms and development of ecotoxicology.
WEEK 2. Human impact on the environment. The division of pollutants per site pollution .Persistence and detoxication.
WEEK 3. Classification of poisons. Factors that determine the movement and distribution of pollutants
WEEK 4. The pathophysiological effects of poisoning. The mode of action of poisons. Absorption and distribution of xenobiotics in the body
WEEK 5. Molecular-cellular aspects of toxicity.Transport of toxicants through the cell membrane
WEEK 6. Biotransformation. Biodynamics and excretion of toxic substances.
WEEK 7. Biological degradation of the toxic substances in the environment. Transport mechanisms in the environment.Bioaccumulation, bioconcentration and biomagnification
WEEK 8. Partial exam
WEEK 9. Assessment of genotoxicity.Uv radiation and marine phytoplankton. Introduction to analytical methods in ecotoxicology. Qualitative analytical methods for determination of toxicants
WEEK 10. Quantitative analytical methods for the determination of toxicants
WEEK 11. The mechanism of toxicity and detection of nitrate, nitrite and ammonia
WEEK 12. Methods for detection of cyanide and cyanide glycoside
WEEK 13. The mechanism of toxicity of heavy metals
WEEK 14. Methods of biomonitoring, analysis of residues (determining MRL). Biological determination of toxins from shellfish
WEEK 15. Partial exam

Format of instruction: lectures, seminars and workshops, independent assignments

Student responsibilities: Class attendance of at least 80% of all lectures and seminars.

Monitoring student work: Class attendance, Essay, Research, Preliminary exam, Written exam, Seminar paper, (other)

Learning outcomes at the level of the programme to which the course contributes:
- Compile and apply advanced knowledge of natural and technical sciences, particularly chemical engineering and environmental engineering in solving scientific, professional and general social problems.
- Correlate expert knowledge from chemistry, chemical engineering and material engineering with awareness of influence on society, economy and environment.
- Utilise advanced laboratory procedures and instruments for synthesis of new products, create sustainable processes, and solve problems of water, air and soil pollution.
- Apply tools, methods and standards for monitoring and assessing the quality of processes and products, as well as their environmental impact, and to predict potential risks in working with technological processes and developing products.
- Create a critical analysis, evaluation and interpretation of personal results, and compare them with existing data in scientific and expert literature
- Investigate and analyse implementation of innovative and incoming chemical technologies in multidisciplinary environment
- Demonstrate independence and reliability in independent work, as well as effectiveness, reliability and adaptability in team work
- Outline results of independent and teamwork in a written and oral form to non-experts and experts in a clear and coherent way.
- Communicate with the scientific and professional community, as well as society in general in local and international surroundings

Expected learning outcomes at the level of the course (3 to 10 learning outcomes):
- Outline basic concepts and relationships in the ecosystem,
- Define types of pollution and mechanisms through which they enter the environment
- Explain activity mechanisms of different types of xenobiotics,
- Discuss molecular-cellular aspects of toxicity,
- Discuss the role of bioindicators and biomarkers for determining the condition of environmental pollution in land and water ecosystems .

1. Outline basic concepts and relationships in the ecosystem
2. Define types of pollution and mechanisms through which they enter the environment
3. Explain activity mechanisms of different types of xenobiotics
4. Discuss molecular-cellular aspects of toxicity
5. Discuss the role of bioindicators and biomarkers for determining the condition of environmental pollution in land and water ecosystems

1. Handbook of ecotoxicology, Hoffman, D.J., Rattner,B.A., Burton, G.A.jr. , Cairns, J.,jr., CRC Press, 1995.
2. Toxicology : a primer on toxicology principles and applications, Kamrin, M.A., Lewis publishers, 1988.
3. Ecotoxicology, lectures, J. Maršić Lučić, ppt,
4. Principles of ecotoxicology, Walker,C.H., Hopkin, S.P., Sibly, R.M.and Peakall,D.B., Taylor & Francis publ., 1997.

Izborni predmeti - Regular studij - Chemical and Environmental Technology