1. komponenta

Lecture type	Total
Lectures	30
Laboratory exercises	15

* Load is given in academic hour (1 academic hour = 45 minutes)

COURSE OBJECTIVES: To introduce chemical engineering students to the fundamentals of biochemical engineering. Acquisition of practical and theoretical knowledge necessary for bioprocess development.
COURSE CONTENT (SYLLABUS)
1. Introduction (definition and scope of bioprocess engineering, chemical and biochemical process engineering, similarities, differences and special features).
2. Basic concepts: Bioprocess, biotransformation, fermentation, biosynthesis, cellular metabolism.
3. Biocatalysis: theory.
4. Enzyme kinetics: kinetic model
5. Biocatalysts: Forms, preparation 6. Heterogeneous biocatalysts: Immobilisation methods
7. Conditions for growth of microorganisms
8. Growth kinetics of microorganisms
9. Multi-enzymatic processes 10. Bioreactors
11. Technical requirements for bioreactor design 12. Separation processes (down stream processing): separation processes solid, liquid
13. Separation processes: Cell disruption processes; bioproduct concentration
14. Industrial biotransformations 1 (student presentations on a specific topic).
15. Industrial biotransformations 2 (student presentations on a specific topic)
ENROLLMENT REQUIREMENTS AND/ OR REQUIRED ACCESS COMPETENCIES FOR THE COURSE: Mass and energy balance, unit operations, fluid mechanics, reaction engineering, microbiology.
DEVELOPMENT OF GENERAL AND SPECIFIC COMPETENCIES OF STUDENTS:
General: Acquisition of basic and advanced knowledge required by chemical engineers for bioprocess development.
Specific: Distinguish between chemical processes and bioprocesses; understand the specifics of biological material; understand the specifics of biocatalysis; acquire practical skills in handling biological material.
STUDENT RESPONSIBILITIES
Students are required to attend lectures and laboratory exercises and submit a report on the laboratory exercises at the end of the semester.
FORMAT OF TEACHING: Lectures, laboratory exercises, classroom computer exercises (SCIENTIST).
SURVEILLANCE STUDENT WORK: 1. Partial exam or 2. Written exam
METHOD OF MONITORING THE QUALITY AND PERFORMANCE OF COURSES: student survey.
LEARNING OUTCOMES AT THE LEVEL OF OF COURSE (4-8):
1. Master the fundamentals of bioprocess engineering.
2. Understand the characteristics of biological materials.
3. Understand the theory of biocatalysis
4. Identify the advantages and disadvantages of biocatalysts
5. Master the engineering strategy of bioprocess development.
6. Acquire knowledge of the fundamentals of bioseparation process.
7. Understand the specifics of bioseparation processes.
LEARN OUTCOMES AT THE LEVEL OF THE PROGRAMME STUDY:
1. interpret the advantages and disadvantages of the latest achievements in the field of chemical engineering
2. evaluate the application of new technologies, i.e. emerging technologies
3. methodically classify knowledge from different fields and systematically draw conclusions 4. demonstrate the ability to work and communicate effectively in a national and international environment.

1. J.E.Bailey, D.F.Ollis, Biochemical Engineering Fundamentals McGraw-Hill (1986).
   A.Scragg ed. Biotechnology for Engineers - Biological Systems in Technological Processes, Ellis Horwood Limited, Chichester, (1988)
   K.van't Riet, J.Tramper, Basic Bioreactor Design, M.Dekker, New York, (1991)
   H.W.Blanch, D.S.Clark, Biochemical Engineering, Marcel Dekker, New York, (1996),
2. A.Liese, K. Seelbach, C.Wandrey, eds. Industrial Biotransformations, Wiley VCH Verlag GmbH&Co.KgaA, Weinheim, 2nd edition 2006.
   A.S,.Bommarius, B.R.Riebel, Biocatalysis-Fundamentals amd Applications, Wiley VCH Verlag GmbH&Co.KgaA, Weinheim, 1.st reprint 2004, 2nd reprint 2008
   Predavanja nastavnika u Power-Point prezentaciji
   Radovi u časopisima po potrebi,

Mandatory course - Regular modul - Chemical Engineering in Environmental Protection